Poly(ADP-Ribose) polymerases (PARPs) are enzymes that metabolize NAD+.PARP1 and PARP10 were previously implicated in the regulation of autophagy.Here we showed that cytosolic electron-dense particles appear in the cytoplasm of C2C12 myoblasts in which PARP2 is silenced by shRNA.The cytosolic electron-dense bodies resemble autophagic vesicles and, i
New insights into the evolution of the surface antennal sensory equipment in free-living and cave-dwelling beetles (Leiodidae: Leptodirini)
The stable environment of subterranean realms is characterized by constant darkness, temperature and humidity, and scarcity of resources.This led to similar adaptations in Belt different lineages of animals, such as the reduction of eyes and pigmentation.It is common textbook knowledge that blindness in cave insects is compensated for by transforma
Feeding habitat of the understory arboreal snail Tikoconus costarricanus (Stylommatophora: Euconulidae) in a tropical montane wet forest, Costa Rica
Introduction: The feeding habitats of land snails are essential for their survival.Some are little known, for example the upper surface of leaves, habitat of tropical arboreal and shrub snails.Objective: To analyze the feeding behavior and preferences in the feeding habitat of the tropical snail Tikoconus costarricanus.Methods: In a humid montane t
Cystic neuroendocrine tumor of the pancreas a challenging clinical diagnosis!
Cystic pancreatic neuroendocrine tumor accounts for 13-17% of pancreatic neuroendocrine tumors and 9-10% of resected cystic tumors.This unusual variant can make clinical diagnosis particularly challenging.A SUPER SKINNY DAILY TREATMENT 28-year-old female patient presented with abdominal pain and dyspepsia.General and physical examination was unrema